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Learn more about Smith-Magenis Syndrome (SMS)

To find out more about potential treatment options for nighttime sleep disturbances in SMS or get more information about a genetic test
please sign up for a health educator to reach out to you or call 833.433.4331.

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About Smith-Magenis Syndrome

SMS is a developmental disorder that is most often caused by a deletion in chromosome 17p11.2 that encompasses the retinoic acid-induced 1 (RAI1) gene.

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Autism & SMS

Alterations in RAI1 copy number has been also linked to a number of neurodevelopmental disorders including Autism Spectrum Disorder (Autism). In fact, 90% of SMS patients meet diagnostic criteria for Autism at one point in their lives.

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SMS & Sleep Disturbance

One of the most common symptoms of SMS is a severe sleep disorder associated with significant disruption in the lives of patients and their families.

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Living With SMS

Patients with SMS present with a number of physical, mental and behavioral problems.

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SMS & Sleep Disturbance

Access Tools and information shared by professionals and parents who have stood where you stand.

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To find out more about potential treatment options for nighttime sleep disturbances in SMS or arrange for a genetic test
please sign up for a health educator to reach out to you or call 833.433.4331